Cancer-miRNA Regulatory Network

Compendium of miRNA Target Genes

Download FIRM

Citation

AD Lung Beer Cluster Number 35 (82 genes) This page contains all miRNA mediated regulation and functional enrichment for AD Lung Beer cluster number 35. Information about lung cancer can be found on Wikipedia, and further information about the "AD Lung Beer" dataset can be found in Beer et al., 2002. Inferred miRNA Mediated Regulation Weeder-miRvestigator PITA TargetScan zzz999 hsa-mir-222 zzz999 Gene Ontology Enrichment GO ID GO Term Annotated Genes in Cluster GO:0001501 skeletal system development 9 GO:0001525 angiogenesis 8 GO:0001568 blood vessel development 12 GO:0001837 epithelial to mesenchymal transition 4 GO:0001944 vasculature development 13 GO:0002455 humoral immune response mediated by circulating immunoglobulin 4 GO:0002576 platelet degranulation 5 GO:0003008 system process 25 GO:0003012 muscle system process 12 GO:0003013 circulatory system process 9 GO:0006928 cellular component movement 14 GO:0006936 muscle contraction 11 GO:0006956 complement activation 5 GO:0006958 complement activation, classical pathway 4 GO:0006959 humoral immune response 5 GO:0007155 cell adhesion 17 GO:0007166 cell surface receptor linked signaling pathway 26 GO:0007275 multicellular organismal development 39 GO:0008015 blood circulation 9 GO:0008283 cell proliferation 21 GO:0008284 positive regulation of cell proliferation 11 GO:0009611 response to wounding 17 GO:0009653 anatomical structure morphogenesis 24 GO:0009887 organ morphogenesis 12 GO:0010463 mesenchymal cell proliferation 4 GO:0014031 mesenchymal cell development 5 GO:0022601 menstrual cycle phase 2 GO:0022610 biological adhesion 17 GO:0030029 actin filament-based process 9 GO:0030198 extracellular matrix organization 6 GO:0030323 respiratory tube development 7 GO:0030324 lung development 7 GO:0030539 male genitalia development 3 GO:0031069 hair follicle morphogenesis 3 GO:0032501 multicellular organismal process 55 GO:0032502 developmental process 39 GO:0033002 muscle cell proliferation 5 GO:0040007 growth 15 GO:0042060 wound healing 13 GO:0042063 gliogenesis 6 GO:0042127 regulation of cell proliferation 18 GO:0043062 extracellular structure organization 7 GO:0043627 response to estrogen stimulus 6 GO:0048144 fibroblast proliferation 5 GO:0048145 regulation of fibroblast proliferation 5 GO:0048146 positive regulation of fibroblast proliferation 4 GO:0048513 organ development 25 GO:0048514 blood vessel morphogenesis 9 GO:0048731 system development 35 GO:0048762 mesenchymal cell differentiation 6 GO:0048856 anatomical structure development 36 GO:0050673 epithelial cell proliferation 7 GO:0050678 regulation of epithelial cell proliferation 7 GO:0065007 biological regulation 62 GO:0065008 regulation of biological quality 32 Overlap Between miRNA Target Genes and Enriched Gene Ontology Annotations miRNA Method GO ID GO Term Overlap GO Annotated Genes Cluster Size miRNA Targets Genes P-Value hsa-mir-222 PITA GO:0001501 skeletal system development 0 9 82 7 0.5714222 hsa-mir-222 PITA GO:0001525 angiogenesis 1 8 82 7 0.136824 hsa-mir-222 PITA GO:0001568 blood vessel development 1 12 82 7 0.2708196 hsa-mir-222 PITA GO:0001837 epithelial to mesenchymal transition 0 4 82 7 0.3050839 hsa-mir-222 PITA GO:0001944 vasculature development 1 13 82 7 0.3062932 hsa-mir-222 PITA GO:0002455 humoral immune response mediated by circulating immunoglobulin 0 4 82 7 0.3050839 hsa-mir-222 PITA GO:0002576 platelet degranulation 0 5 82 7 0.3674481 hsa-mir-222 PITA GO:0003008 system process 3 25 82 7 0.122446 hsa-mir-222 PITA GO:0003012 muscle system process 0 12 82 7 0.6846787 hsa-mir-222 PITA GO:0003013 circulatory system process 1 9 82 7 0.1684311 hsa-mir-222 PITA GO:0006928 cellular component movement 1 14 82 7 0.3419383 hsa-mir-222 PITA GO:0006936 muscle contraction 0 11 82 7 0.6501905 hsa-mir-222 PITA GO:0006956 complement activation 0 5 82 7 0.3674481 hsa-mir-222 PITA GO:0006958 complement activation, classical pathway 0 4 82 7 0.3050839 hsa-mir-222 PITA GO:0006959 humoral immune response 0 5 82 7 0.3674481 hsa-mir-222 PITA GO:0007155 cell adhesion 3 17 82 7 0.03094709 hsa-mir-222 PITA GO:0007166 cell surface receptor linked signaling pathway 2 26 82 7 0.3904037 hsa-mir-222 PITA GO:0007275 multicellular organismal development 3 39 82 7 0.4447002 hsa-mir-222 PITA GO:0008015 blood circulation 1 9 82 7 0.1684311 hsa-mir-222 PITA GO:0008283 cell proliferation 1 21 82 7 0.578536 hsa-mir-222 PITA GO:0008284 positive regulation of cell proliferation 0 11 82 7 0.6501905 hsa-mir-222 PITA GO:0009611 response to wounding 1 17 82 7 0.4475261 hsa-mir-222 PITA GO:0009653 anatomical structure morphogenesis 2 24 82 7 0.3327436 hsa-mir-222 PITA GO:0009887 organ morphogenesis 0 12 82 7 0.6846787 hsa-mir-222 PITA GO:0010463 mesenchymal cell proliferation 0 4 82 7 0.3050839 hsa-mir-222 PITA GO:0014031 mesenchymal cell development 0 5 82 7 0.3674481 hsa-mir-222 PITA GO:0022601 menstrual cycle phase 0 2 82 7 0.1644083 hsa-mir-222 PITA GO:0022610 biological adhesion 3 17 82 7 0.03094709 hsa-mir-222 PITA GO:0030029 actin filament-based process 2 9 82 7 0.02619897 hsa-mir-222 PITA GO:0030198 extracellular matrix organization 1 6 82 7 0.07992457 hsa-mir-222 PITA GO:0030323 respiratory tube development 0 7 82 7 0.4779177 hsa-mir-222 PITA GO:0030324 lung development 0 7 82 7 0.4779177 hsa-mir-222 PITA GO:0030539 male genitalia development 0 3 82 7 0.2375226 hsa-mir-222 PITA GO:0031069 hair follicle morphogenesis 0 3 82 7 0.2375226 hsa-mir-222 PITA GO:0032501 multicellular organismal process 5 55 82 7 0.2592614 hsa-mir-222 PITA GO:0032502 developmental process 3 39 82 7 0.4447002 hsa-mir-222 PITA GO:0033002 muscle cell proliferation 0 5 82 7 0.3674481 hsa-mir-222 PITA GO:0040007 growth 2 15 82 7 0.1107699 hsa-mir-222 PITA GO:0042060 wound healing 1 13 82 7 0.3062932 hsa-mir-222 PITA GO:0042063 gliogenesis 0 6 82 7 0.4249529 hsa-mir-222 PITA GO:0042127 regulation of cell proliferation 0 18 82 7 0.8365976 hsa-mir-222 PITA GO:0043062 extracellular structure organization 1 7 82 7 0.1071636 hsa-mir-222 PITA GO:0043627 response to estrogen stimulus 1 6 82 7 0.07992457 hsa-mir-222 PITA GO:0048144 fibroblast proliferation 0 5 82 7 0.3674481 hsa-mir-222 PITA GO:0048145 regulation of fibroblast proliferation 0 5 82 7 0.3674481 hsa-mir-222 PITA GO:0048146 positive regulation of fibroblast proliferation 0 4 82 7 0.3050839 hsa-mir-222 PITA GO:0048513 organ development 1 25 82 7 0.6918288 hsa-mir-222 PITA GO:0048514 blood vessel morphogenesis 1 9 82 7 0.1684311 hsa-mir-222 PITA GO:0048731 system development 2 35 82 7 0.6445327 hsa-mir-222 PITA GO:0048762 mesenchymal cell differentiation 0 6 82 7 0.4249529 hsa-mir-222 PITA GO:0048856 anatomical structure development 2 36 82 7 0.6700722 hsa-mir-222 PITA GO:0050673 epithelial cell proliferation 0 7 82 7 0.4779177 hsa-mir-222 PITA GO:0050678 regulation of epithelial cell proliferation 0 7 82 7 0.4779177 hsa-mir-222 PITA GO:0065007 biological regulation 6 62 82 7 0.1293602 hsa-mir-222 PITA GO:0065008 regulation of biological quality 4 32 82 7 0.07769068

Need help? Please contact cplaisier(at)systemsbiology.org if you have any questions, comments or concerns. Developed at the Institute for Systems Biology in the Baliga Lab.